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State Profile

South Carolina

Restricted Practice Authority

Credential
APRN
Est. Fees
$515
CE Hours
30 hrs/cycle
Controlled Subs
Sched III-V; II very restricted
Restricted Practice Authority
Very restricted Schedule II. Supervision agreement required. Compact state.
Step-by-step application for South Carolina
1
Verify your active RN license
Hold a current RN license in South Carolina or a valid compact multistate RN license. Board: llr.sc.gov/nurse
2
Complete an accredited MSN or DNP
CCNE or ACEN accredited with your NP specialty focus and at least 500 supervised clinical hours.
3
Pass your national certification exam
AANP or ANCC in your specialty. For PMHNP: ANCC PMHNP-BC only.
4
Submit your APRN application
Apply online to the South Carolina Board of Nursing. Fee: $515. Transcripts and certification sent directly to the board.
5
Complete background check
Fingerprinting through an approved vendor. Allow 2–4 weeks for processing.
6
Establish physician supervision agreement
Required before prescribing in South Carolina. Must be on file with the board.
7
Apply for DEA registration
Apply at dea.gov after state licensure. $888 every 3 years. Register with SC PDMP within 30 days.

Visit South Carolina Board of Nursing ↗

Open a module for South Carolina requirements
NP PRACTICEACADEMY
Verified from official state boards · Updated 2026