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State Profile
Missouri
Restricted Practice Authority
Credential
APRN
Est. Fees
$390
CE Hours
None required
Controlled Subs
Sched III-V; II very limited
Restricted Practice Authority
No CE beyond national cert. Collaborative Practice Arrangements required. Very limited Schedule II.
Step-by-step application for Missouri
1
Verify your active RN license
Hold a current RN license in Missouri or a valid compact multistate RN license. Board: pr.mo.gov
2
Complete an accredited MSN or DNP
CCNE or ACEN accredited with your NP specialty focus and at least 500 supervised clinical hours.
3
Pass your national certification exam
AANP or ANCC in your specialty. For PMHNP: ANCC PMHNP-BC only.
4
Submit your APRN application
Apply online to the Missouri State Board of Nursing. Fee: $390. Transcripts and certification sent directly to the board.
5
Complete background check
Fingerprinting through an approved vendor. Allow 2–4 weeks for processing.
6
Establish Collaborative Practice Arrangement
Required before prescribing in Missouri. Must be on file with the board before you see patients.
7
Apply for DEA registration
Apply at dea.gov after state licensure. $888 every 3 years. Register with MO PDMP within 30 days.
Visit Missouri Board of Nursing ↗
Open a module for Missouri requirements
NP PRACTICEACADEMY
Verified from official state boards · Updated 2026